American Radium Society Appropriate Use Criteria: Radiation Therapy for Limited-Stage SCLC 2020

نویسندگان

چکیده

IntroductionCombined modality therapy with concurrent chemotherapy and radiation has long been the standard of care for limited-stage SCLC (LS-SCLC). However, there is controversy over best combined practices LS-SCLC. To address these controversies, American Radium Society (ARS) Thoracic Appropriate Use Criteria (AUC) Committee have developed updated consensus guidelines treatment LS-SCLC.MethodsThe ARS AUC are evidence-based specific clinical conditions that reviewed by a multidisciplinary expert panel. The include review analysis current evidence application methodology (modified Delphi) to rate appropriateness treatments recommended panel Agreement or was defined as less than equal 3 rating points from median. ratings recommendations were then vetted Executive subject public comment before finalization.ResultsThe committee multiple There strong patients unresectable LS-SCLC should receive delivered either once twice daily. For medically inoperable T1-T2N0 LS-SCLC, chemoradiation stereotactic body followed adjuvant reasonable option. continues recommend whole-brain prophylactic cranial irradiation after response agreement hippocampal avoidance programmed cell death protein-1/programmed death-ligand 1–directed immune not be routinely administered outside context trials at this time.ConclusionsThe provide aim groundwork trials.

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2021

ISSN: ['1556-0864', '1556-1380']

DOI: https://doi.org/10.1016/j.jtho.2020.10.020